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. 2000 Jun;156(6):2123–2133. doi: 10.1016/S0002-9440(10)65083-3

Figure 1.

Figure 1.

Representative foci microdissected from case G2 and spatial distribution of heterogeneous genetic patterns. A: Gross photo of the specimen showing the histology sections taken. B and C: Low power views of the section B and section C showing the microdissected foci and the distribution of heterogeneous LOH. T6,T12, hyperplasia; T1-T3, T7-T10, T15, foci of severe ductal dysplasia; T4, T5, T11, invasive foci; dotted lines divide areas with divergent genetic changes. D–I: Representative histology. D: T12, pap HP. Original magnification, ×100. E and F: T1, severe ductal dysplasia. Original magnifications: E, ×2.5; F, ×100. G and H: T15, severe ductal dysplasia. Original magnifications: G, ×10; H, ×100. I: T5, invasive focus. Original magnification, ×50.