Figure 5.

Electron microscopy of cells surrounded by the duct-like structures and those constituting the structures. A: Some of the cells surrounded by the duct-like structures have numerous glycogen rosettes, tight junctions with desmosomes (arrows), and bile canaliculi-like structures with microvilli. B and C: Cells constituting duct-like structures show a large nucleus-cytoplasm ratio, a lumen structure with short microvilli (arrows in B), and juxtaluminal junctional complexes (arrow in C). The nuclei, which are notched in some cells, are located in the basal region of the cells. C: High magnification of the boxed area in B. Original magnifications, ×12,000 (A), ×1500 (B), ×6000 (C). Scale bars, 1 μm (A and C) and 5 μm (B).