Histological features of LM and LMS as well as immunohistochemical staining for Ki-67, PCNA, and cell-cycle regulator proteins. Streptavidin-biotin peroxidase method with hematoxylin counterstain; original magnification, ×700. PCNA, proliferating cell nuclear antigen; cyc A, cyclin A; cyc E, cyclin E; cdk, cyclin-dependent kinase 2; CAK, cdk-activating kinase.