Table 1.
Incidence of Mice Euthanized Prematurely and Age at Death
| 15–17 Weeks of Age Group | ||||||
|---|---|---|---|---|---|---|
| ret/PTC1+ p53+/+ | ret/PTC1− p53+/+ | ret/PTC1+ p53+/− | ret/PTC1− p53+/− | ret/PTC1+ p53−/− | ret/PTC1− p53−/− | |
| Early removal | 0% | 0% | 0% | 5% | 55% | 29% |
| (0/22) | (0/22) | (0/22) | (1/22) | (12/22) | (6/21) | |
| Age range | 103–120 | 103–111 | 104–109 | 91–115 | 62–120 | 76–117 |
| Mean age | 108 | 106 | 106 | 106 | 93 | 102 |
| 28 Weeks of Age Group | ||||||
|---|---|---|---|---|---|---|
| ret/PTC1+ p53+/+ | ret/PTC1− p53+/+ | ret/PTC1+ p53+/− | ret/PTC1− p53+/− | ret/PTC1+ p53−/− | ret/PTC1− p53−/− | |
| Early removal | 15% | 0% | 17% | 0% | 100% | 92% |
| (2/13) | (0/12) | (2/12) | (0/12) | (14/14) | (11/12) | |
| Age range | 49–204 | 190–197 | 67–194 | 190–195 | 49–117 | 82–190 |
| Mean age | 174 | 192 | 175 | 190 | 92 | 125 |
Age data are stated in days.