Table 1.

Tissue Involvement by Y79 Retinoblastoma in Mice

Site	Weeks
	2	3	4	5	6	7	8	9
Vitreous	+2 /3	+3 /3	+3 /3	+3 /3	+6 /6	+3 /3	+2 /2	+1 /1
Retina	−	+2 /3	+2 /3	+3 /3	+6 /6	+3 /3	+2 /2	+1 /1
Subretinal space	−	+2 /3	+2 /3	+3 /3	+6 /6	+3 /3	+2 /2	+1 /1
Iris	−	−	−	−	−	−	+1 /2	+1 /1
Lens	−	−	−	−	−	−	−	+1 /1
Anterior chamber	−	−	−	−	−	+1 /3	+2 /2	+1 /1
Choroid	−	−	+1 /3	+3 /3	+4 /6	+3 /3	+2 /2	+1 /1
Optic nerve	−	−	−	+1 /3	+3 /6	+2 /3	+2 /2	+1 /1
Extraocular	−	−	−	−	−	−	+1 /2	+1 /1
Brain	−	−	−	+2 /3	+4 /6	+1 /3	+2 /2	+1 /1
Contralateral eye	−	−	−	−	−	−	+1 /2	+1 /1

Mice were necropsied and the tissues examined histologically as described in Methods. The data are expressed as the number of animals that were positive for tumor at each site/total number of animals examined.

−, tissues without evidence of tumor in any of the examined animals.