Table 2.
Incidence of Hepatic Lesions in TT and CC Mice
| Hepatic lesions | TT mice | CC mice | P value | ||
|---|---|---|---|---|---|
| Animals with lesions | Percentage | Animals with lesions | Percentage | ||
| First experiment | |||||
| LCD | 19 /64 | 29.7 | 19 /150 | 12.7 | 3.3 × 10−3 |
| BLCN | 37 /64 | 57.9 | 35 /150 | 23.3 | 1.5 × 10−6 |
| HA | 26 /64 | 40.6 | 15 /150 | 10.0 | 6.6 × 10−7 |
| HC | 32 /64 | 50.0 | 19 /150 | 12.7 | 1.7 × 10−8 |
| Second experiment | |||||
| LCD | 14 /25 | 56.0 | 6 /50 | 12.0 | 9.7 × 10−5 |
| BLCN | 9 /25 | 36.0 | 11 /50 | 22.0 | 1.5 × 10−1 |
| HA | 8 /25 | 32.0 | 4 /50 | 8.0 | 1.1 × 10−2 |
| HC | 8 /25 | 32.0 | 2 /50 | 4.0 | 1.7 × 10−3 |
TT, tat-transgenic mice; CC, control BDF mice; LCD, liver cell dysplasia; BLCN, basophilic liver cell nodules; HA, hepatocellular adenomas; HC, hepatocellular carcinomas. P value was obtained by Fisher’s exact test.