Table 3.
Summary of the Results on Proliferation Index, Apoptosis, In Vitro Survival, and Volume of the Tumor (cm3) in Seminomas With and Without a Restricted 12p Amplification/RAS Mutation
| Wild-type RAS | Mutant RAS | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Proliferation index | Apoptosis | In vitro survival | Tumor volume | Proliferation index | Apoptosis | In vitro survival | Tumor volume | |||||
| + | − | + | − | + | − | + | − | |||||
| 12p-ampl. | ||||||||||||
| − | 34.5 (10.5) | 9 | 4 | 1 | 11 | 256 (173) | 30.8 (3.1) | 1 | 5 | 6 | 0 | 121 (88) |
| + | 29.7 (15.3) | 0 | 9 | 4 | 0 | 246 (294) | NA | NA | NA | NA | NA | NA |
Abbreviations: 12p-ampl., restricted 12p amplification; +, present; −, absent; NA, not available. Standard deviations are indicated between brackets.