Figure 7.

Primed neutrophils aged in culture for 12 hours with N IgG or ANCA. Apoptosis was assessed by morphology and expressed as a percentage of the total number of cells that were apoptotic (A). Macrophage interaction experiments were performed using murine peritoneal-derived macrophages, and data were expressed by the phagocytic index (B). Data are means ± SD of three experiments. There were significantly more apoptotic cells when they were incubated with ANCA than when they were incubated with normal IgG (A). However, there was no difference in the number of cells phagocytosed when they were incubated with ANCA or normal IgG (B) (*P < 0.05).