Table 1.
Comparative Genomic Hybridization of Type A Thymoma (Medullary Thymoma), Type B3 Thymoma (Well-Differentiated Thymic Carcinoma), and Primary Thymic Squamous Cell Carcinoma: Patient Data and Chromosomal Gains and Losses Detected by CGH
| Case | Age | Sex | WHO Type | Stage | MG | rev ish enh | rev ish dim |
|---|---|---|---|---|---|---|---|
| 1 | 65 | m | A | I | ng | — | — |
| 2 | 66 | m | A | I | yes | — | — |
| 3 | 74 | f | A | I | ng | — | — |
| 4 | 60 | f | A | I | no | — | — |
| 5 | 73 | f | A | II | no | — | — |
| 6 | 57 | f | A | I | ng | — | — |
| 7 | 68 | m | A | III | no | — | — |
| 8 | 74 | m | A | II | yes | — | −6p21-pter |
| 9 | 65 | m | A | I | no | — | — |
| 10 | 71 | m | A | I | ng | — | — |
| 11 | 47 | m | A | III | no | — | — |
| 12 | 57 | m | A | I | no | — | — |
| 13 | 46 | m | B3 | IVb | yes | +1q | −6 |
| 48 | m | B3 R | IVb | yes | +1q,+5p,+5cen-q21, +Xq22-qter | −6 | |
| 14 | 45 | m | B3 | III | yes | +1q22-qter, +Xq24-qter | −13q21-q31 |
| 15 | 63 | f | B3 | II | ng | +17q | — |
| 16 | 65 | m | B3 | IVb | yes | +16 | — |
| 17 | 73 | f | B3 | II | yes | +1q | −6 |
| 18 | 42 | f | B3 | ng | yes | +1q | — |
| 19 | 46 | f | B3 | III | yes | +1q, ampl 8p12 | −6,−18q |
| 20 | 63 | m | B3 | IVb | ng | +1q,+7 | — |
| 21 | 29 | m | B3 | II | yes | — | −13q |
| 22 | 42 | f | B3 | II | yes | +1q | −6 |
| 23 | 53 | f | B3 | III | ng | — | −13q21-qter |
| 24 | 61 | m | B3 | ng | ng | +1q | −6 |
| 25 | 47 | f | B3 | II | yes | +1q23-qter | — |
| 26 | 63 | m | B3 | IV | no | +8,+Xq21-qter | −13q |
| 27 | 57 | m | B3 | II | yes | +1q | −6q,−12p, −12cen-12q21 |
| 28 | 63 | m | B3 | III | yes | +1q | −3p, −3q13,−13q14-qter,−16q12-q21 |
| 29 | ng | f | C(TSSC) | ng | ng | +5p,+8q | −3p13-pter, −8p,−5q15-q23 |
| 30 | 57 | f | C(TSSC) | III | ng | — | −3 |
| 61 | f | C(TSSC) R | IVa | ng | — | −3 | |
| 31 | 57 | f | C(TSSC) | ng | ng | — | −6,−16q |
| 32 | 45 | m | C(TSSC) | III | no | +1q,+17q, +18q23 | −16q21-qter,−17p13 |
| 33 | 67 | m | C(TSSC) | III | no | +1q, +3q21-q22 | −2q32-q33,−3p,−9,−13cen-q31,−16q,−17p13 |
| 34 | 63 | m | C(TSSC) | II | no | +1q,+5,+18 | −6,−13q, −16q |
| 35 | 43 | m | C(TSSC) | ng | no | — | −16q |
| 36 | 64 | f | C(TSSC) | III | no | +1q,+8,+17q,+18 | −6, −16q,−17p |
| 37 | 72 | f | C(TSSC) | ng | no | +1q,+5q33, +14q22-qter,+15,+17q | −6q |
Abbreviations: m, male; f, female; WHO type, type of thymoma according to the WHO classification 1 ; TSSC, primary thymic squamous cell carcinoma; R, recurrent tumor; stage, stage of thymoma according to Masaoka 28 ; MG, myasthenia gravis; ng, not given; rev ish enh, chromosomal gains detected by CGH; rev ish dim, chromosomal losses detected by CGH.