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Photomicrographs of representative lungs (n = 6 for each genotype) from mice 14 days after bleomycin treatment stained with Masson’s trichrome. A: u-PA−/− lung showing extensive area of fibrosis (f); original magnification, ×100. B: u-PAR−/− lung showing focal areas of fibrosis (f) surrounded by normal alveoli; original magnification, ×100. C: t-PA−/− lung showing areas of fibrosis (f) surrounded by areas of extensive intra-alveolar hemorrhage (h); original magnification, ×100.
