Figure 4.

Photomicrographs of representative mice lungs (n = 3 for each genotype) treated with bleomycin and immunostained with an anti-fibrin (ogen) antibody. A: WT lung 14 days after treatment showing few areas of fibrin deposition (arrows); original magnification, ×100. B: Pg^−/− lung 7 days after treatment showing extensive fibrin deposition (brown aggregates); original magnification, ×40. C: Pg^−/− lung 14 days after treatment showing extensive fibrin deposition (arrows) associated with areas of fibrosis (f); original magnification, ×200.