Table 2.
Total Lung Macrophage Levels Post-Bleomycin Treatment (×106, n = 6, mean ± SE)
| Genotype | Day 0* | Day 3 | Day 5 | Day 7 | Day 9 |
|---|---|---|---|---|---|
| WT | 2.87 ± 0.52 | 5.25 ± 0.90 | 8.68 ± 0.60 | 5.42 ± 0.70 | 5.45 ± 0.50 |
| Pg−/− | 2.47 ± 0.43 | 3.10 ± 0.30 | 4.86 ± 0.40 | 3.50 ± 0.60 | 4.68 ± 1.00 |
| u-PA−/− | 3.85 ± 0.30 | 2.30 ± 0.70 | 5.62 ± 1.00 | 5.25 ± 0.80 | 4.28 ± 0.60 |
| u-PAR−/− | 4.80 ± 0.60 | 3.87 ± 0.70 | 3.40 ± 0.40 | 3.95 ± 0.70 | 6.22 ± 0.50 |
| t-PA−/− | 3.81 ± 0.61 | 3.87 ± 0.40 | 5.15 ± 0.80 | 6.47 ± 0.50 | 7.48 ± 0.30 |
*Baseline macrophage levels, representing macrophages present in lungs of animals that did not receive any treatment.