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. 2001 Jan;158(1):293–297. doi: 10.1016/S0002-9440(10)63968-5

Figure 2.

Figure 2.

Tissue levels of total NPs (F-ring plus D/E-ring compounds) (A) or F4-NPs and F2-IsoPs (B) were stratified by brain region for AD patients and controls. Values are means ± SEM. A: Two-way ANOVA for total NP’s was significant for AD patients versus controls (P < 0.0001) and for brain region (P < 0.05). Repeated pairs analysis with Bonferroni’s correction showed that total NP’s were significantly greater in cerebral cortical regions in AD patients compared to controls (*, P < 0.05). B: Two-way ANOVA of tissue levels of F-ring compounds were significantly different between AD patients and controls for both F4-NPs (P < 0001) and F2-IsoPs (P < 0.05); however, only the F4-NPs were significantly associated with brain region (P < 0.05).