Table 3.
Heat-Shock Protein (HSP) 70 Results of the Control Subjects, Depressed Patients, and Steroid-Treated Group
| Patient no. | CA1/2 | CA3 | CA4 | DG | Sub | EC | Cx | Remarks | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Controls | ||||||||||||||||
| 1. 92-011 | − | − | − | −P | − | nd | nd | |||||||||
| 2. 94-035 | − | nd | +/−C | − | − | − | +II/III | |||||||||
| 3. 94-0118f | +/−N | +NC,S | +NC | −N | +/−N | +/−N | +II/III C | |||||||||
| 4. 96-014 | +/−(1x) | +/−C | − | − | − | nd | − | |||||||||
| 5. 96-10 | − | − | − | − | − | − | − | |||||||||
| 6. 96-013 | − | +/−N | +/−N | − | − | +/−C | +/−N | |||||||||
| 7. 93-061 | nd | − | − | − | − | − | +/−N | |||||||||
| 8. 95-106 | +/−N | −NC | −S, R\ {Tc}− | − | − | − | − | |||||||||
| 9. 94-123 | − | +/−C | +/−N | nd | − | − | − | |||||||||
| 10. 90-086 | − | − | − | − | − | − | − | |||||||||
| 11. 95-093 | − | +/−NC | +/−C | −P | nd | nd | II/III: +/−C | |||||||||
| 12. 94-076 | − | − | − | −P | − | − | − | Infiltrates/bleeding in sulcus | ||||||||
| 13. 92-016 | − | +/−C | +/−C, S | − | − | − | − | |||||||||
| 14. 89-045 | − | − | − | −P | − | − | − | |||||||||
| 15. 82-018 | − | − | − | − | − | − | − | |||||||||
| Depressed patients | ||||||||||||||||
| 1. 93-076 | nd | − | − | − | nd | nd | − | |||||||||
| 2. 93-090 | − | − | − | −P | − | − | − | |||||||||
| 3. 93-146 | +/−N | +/−N | +C | +/−N | +/−N | +/−N | +/−N | |||||||||
| 4. 92-003 | − | − | − | +/−P | +/−N | +/−A | − | |||||||||
| 5. 94-112f | +/−N,C | +N,C | +N | +/−N,P | +/−N | − | −S | Nuclear staining of some individual DG cells | ||||||||
| 6. 93-054 | +/−C,N | +/−C | +C,S | −P | +/−N | − | +/−C,S | |||||||||
| 7. 90-001 | − | +/−C | − | − | − | − | +/−(2x) | |||||||||
| 8. 94-032 | +/−N | +C,S | +/−C,N | −P | +/−NC | − | +/−II−VG | |||||||||
| 9. 94-094f | +/−N | +C | +/−C | − | +/−N | − | +/− | |||||||||
| 10. 94-017 | − | − | +/−C | +C | +/−N | nd | +/−N | |||||||||
| 11. 94-055 | − | +/−N | +/−C | +/−N | − | − | +II−V,S | |||||||||
| 12. 93-021 | −(N) | +/−C | +/−C | −P | − | − | − | |||||||||
| 13. 95-036 | − | +/−C | +/−C | −P | +/− | − | +/−C,S | |||||||||
| 14. 93-115 | Nd | − | − | − | − | − | +II−V,S | |||||||||
| 15. 91-059 | − | − | −R | − | − | − | − | |||||||||
| Steroid-treated group | ||||||||||||||||
| 1. 86-032 | − | − | − | +/−P | − | − | − | |||||||||
| 2. 83-004 | − | +C | ++C | − | − | − | − | |||||||||
| 3. 95-011f | − | +C | ++C | ++C | − | − | − | |||||||||
| 4. 95-051 | +/−N | +/−C | ++C | − | +/−N | +/−N | +/− | |||||||||
| 5. 93-094 | +/−N,C | ++C | ++C | −P | +C | +/− | − | |||||||||
| 6. 95-054f | +/−N | +/−C | ++C | +C,S | ++C | − | II/III: +/−C,S | Infiltration/bleeding in stratum moleculare; positive cells in DG | ||||||||
| 7. 91-120 | − | − | − | − | − | − | − | |||||||||
| 8. 93-016 | − | − | +C | − | − | − | − | |||||||||
| 9. 95-098 | − | − | − | − | − | − | − | |||||||||
Abbreviations used for HSP scoring: N, neuropil staining; C, cellular, cytoplasmic staining pattern; S, small punctate staining of neuropil; P, presence of small, condensed, pycnotic-like cells in the DG granule layer; 2x; denotes the presence of eg, two positive cells in a subarea that is further devoid of staining; A, cellular staining pattern resembling an apoptotic cell. nd: not determined or not present; II, III or II-V relates to cortical layer II and III, and II through LV respectively.