Comparison of the chromosomal aberrations between small, intermediate, and large prostate cancers, showing the average number (± SEM) of altered chromosomes per patient. The average number of aberrant chromosomes per patient significantly increased with increasing exact tumor volume (Rs = 0.36, P = 0.009). The same was true for the number of chromosomes showing loss or, especially, gain per case (Rs = 0.27, P = 0.05; Rs = 0.48, respectively; P < 0.001).