Table 2.
Frequencies of the Most Common Chromosomal Imbalances Found in Relapse and Nonrelapse Wilms Tumors
| Chromosomal imbalance | Relapse n = 46 | Nonrelapse n = 21 | Fisher’s exact test, P value |
|---|---|---|---|
| +1q | 27 (59%) | 5 (24%) | 0.01* |
| −1p | 7 (15%) | 2 (10%) | 0.91 |
| +12 | 15 (33%) | 7 (33%) | 1.00 |
| −16q | 10 (22%) | 3 (14%) | 0.74 |
| −11p | 5 (13%) | 0 (0%) | 0.17 |
| −22q | 3 (7%) | 1 (5%) | 1.00 |
| +8 | 11 (24%) | 7 (33%) | 0.55 |
| −X | 4 (9%) | 3 (14%) | 0.67 |
*Significant difference. Relative risk of relapse for 1q+ v. 1q− = 4.5 (1.4–14, 95% confidence intervals).