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. 2001 Feb;158(2):627–637. doi: 10.1016/S0002-9440(10)64004-7

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Copyright © 2001, American Society for Investigative Pathology

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Figure 9. — Loss of Galα1-3Gal and vWF from porcine xenografts. Tissues from porcine pulmonary, renal, and cardiac xenografts were assayed for reactivity with GSL I-B₄, a lectin specific for Galα1-3Gal, and mouse anti-porcine vWF. A: Porcine pulmonary tissues taken 15 minutes after transplantation into baboons have markedly less vWF and less reactivity with GSL I-B₄ than porcine pulmonary tissues taken before transplantation (0 minutes). Original magnification, ×400. B: Porcine renal tissues taken 60 minutes after transplantation into baboons have less vWF but only focal or no decrease of Galα1-3Gal based on reactivity with GSL I-B₄ than porcine renal tissues taken before transplantation (0 minutes). Original magnification, ×400. C: Porcine cardiac tissues taken 60 minutes after transplantation into baboons have less vWF but only focal or no decrease of Galα1-3Gal based on reactivity with GSL I-B₄ than porcine cardiac tissues taken before transplantation (0 minutes). Original magnification, ×400.