Figure 5.

Summary of MMP-1 LOH data from all tumors where LOH was detected, using the 72-bp amplicon assay (A) and the 82-bp amplicon assay (B). The “%2G” for each tumor was determined as described in Figures 4 and 5 ▶ ▶ , and is represented here as a bar. Replicate assays are indicated by individual bars. Fifty percent 2G represents no allelic loss, characteristic of normal tissues. The hatched lines represent the imprecision (2 SD) of the estimate of “%2G” in normal heterozygous tissue samples and control blood samples. Tumor samples whose “%2G” was at or exceeded the imprecision limits in both assays were classified as having undergone LOH. Ten tumors lost the 1G allele; two tumors lost the 2G allele.