Table 2.
CA9/CA12 mRNA Expression in CNS and Spinal Cord Tumors, Based on Northern Blot Analysis
| Sample number | Tumor diagnosis | VHL status | CA12 expression* | CA9 expression* |
|---|---|---|---|---|
| 1 | Meningioma | wt | — | 1 |
| 2 | Anaplastic astrocytoma | wt | — | — |
| 3 | Meningioma | wt | 1 | 2 |
| 4 | Meningioma | wt | 1 | 2 |
| 5 | Glioblastoma | wt | 4 | 10 |
| 6 | Glioblastoma | wt | — | — |
| 7 | Glioblastoma | wt | — | — |
| 8 | Astrocytoma | wt | 1 | 4 |
| 9 | Glioblastoma | wt | 2 | — |
| 10 | Cerebellar hemangioblastoma | wt | — | — |
| 11 | Meningioma | wt | 1 | — |
| 12 | Hemangioblastoma | mut | 2 | 2 |
| 13 | Cerebellar hemangioblastoma (VHL-) | mut | 6 | 4 |
| 14 | Cerebellar hemangioblastoma (VHL-) | mut | 6 | 3 |
| 15 | Spinal hemangioblastoma (VHL-) | mut | 2 | 1 |
| 16 | Spinal hemangioblastoma (VHL-) | mut | 3 | 4 |
| 17 | Cerebellar hemangioblastoma (VHL-) | mut | 5 | 4 |
| 18 | Hemangioblastoma (VHL-) | mut | 5 | 6 |
*Intensity of expression is shown in arbitrary units and based on β-actin calibration.