Figure 9.

Cell growth and type I procollagen synthesis by human dermal fibroblasts are reduced on partially degraded collagen gels compared to intact collagen gels. A: Cell growth. Values represent the mean number of cells present at day 4 ± standard errors (n = 5 foreskin isolates and 4 adult isolates). B: Type I procollagen synthesis. Values represent average ng of type I procollagen per ml ± standard errors (n = 5 foreskin isolates and 4 adult isolates). Before assay, culture media volume from the control and treated groups were adjusted to a common cell number (based on the cell counts presented in A). Statistical significance was determined using the Student’s t-test. *, P < 0.05; **, P < 0.01.