Figure 1.

Increased levels of alanine aminotransferase after CCl₄. Levels of alanine aminotransferase (ALT) in the serum of mice lacking plasminogen activators and control (tPA⁺/uPA⁺) littermates demonstrate a nearly 80-fold increase 2 days after a single dose of CCl₄. Thereafter, values return to baseline levels at 7 to 14 days in a similar manner in mice of all genotypes (mean ± SD, n = 7 for each group at 2 days, and n = 3 to 4 at 0, 7, and 14 days; 0 day = no treatment; no statistical significance among groups within each time point).