Figure 2.

Delayed restoration of normal liver appearance after toxic injury in mice lacking plasminogen activators. Visual inspection of livers from mice lacking plasminogen activators and control littermates shows an indistinguishable pale/lacy appearance in all livers 2 days after CCl₄. Although livers of tPA⁺/uPA⁺ and tPA^o mice restore normal appearance at 7 days, uPA^o livers appear mildly abnormal at 14 days, and tPA^o/uPA^o livers display a pronounced pale/lacy appearance at both time points.