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. 2001 Mar;158(3):921–929. doi: 10.1016/S0002-9440(10)64039-4

Figure 6.

Figure 6.

Activity of plasminogen activators after CCl4. Representative zymography demonstrating plasmin-mediated casein lysis by tPA and uPA in liver extracts of gene-targeted mice and control littermates. Injection of CCl4 results in an increase in activity of plasminogen activators in the first 7 days, with no detectable activity at 14 days. Activities of uPA (7 days) and tPA (14 days) are greater than control littermates in liver extracts from mice lacking the functional homologue.