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. Author manuscript; available in PMC: 2008 Jan 1.
Published in final edited form as: Pharmacol Biochem Behav. 2006 Dec 20;86(1):45–54. doi: 10.1016/j.pbb.2006.12.006

Table 2.

Characterization of tropane analogs

Compound DAT/NET ratio DAT/SERT ratio Selectivity
Cocaine 0.0270 0.0856 Nonselective
RTI-126 0.0127 0.0261 Nonselective
RTI-112 0.0222 0.0762 Nonselective
RTI-150 0.0008 0.0018 DAT selective
RTI-336 0.0024 0.0007 DAT selective
RTI-171 0.0035 0.0002 DAT selective
RTI-177 0.0026 0.0005 DAT selective

Relative selectivity of binding to monoamine transporter ligands in rat tissue (Kuhar et al., 1999).