Table 1.
Distribution of Patients’ Clinicopathological Characteristics According to MSI Status
| Characteristic | All patients (n = 109) | MSS/MSI-L (n = 62) | MSI-H (n = 47) | P value* |
|---|---|---|---|---|
| Age (mean-SD) | 66.4–10.1 | 69.3–12.4 | ||
| Class of age, no. (%) | ||||
| <60 | 25 (22.9) | 19 (30.7) | 6 (12.8) | |
| ≥60 | 84 (77.1) | 43 (69.4) | 41 (87.2) | 0.03 |
| Sex, no. (%) | ||||
| Males | 45 (41.3) | 25 (40.3) | 20 (42.6) | |
| Females | 64 (58.7) | 37 (59.7) | 27 (57.5) | 0.8 |
| Pathological stage, no. (%) | ||||
| II | 55 (50.5) | 28 (45.2) | 27 (57.5) | |
| III | 54 (49.5) | 34 (54.8) | 20 (42.6) | 0.2 |
| Grade, no. (%) | ||||
| Well/Moderate | 64 (58.7) | 45 (72.6) | 19 (40.4) | |
| Poor | 45 (41.3) | 17 (27.4) | 28 (59.6) | 0.0009 |
| Histological type, no. (%) | ||||
| Adenocarcinoma NOS | 77 (70.6) | 52 (83.9) | 25 (53.2) | |
| Mucoid adenocarcinoma | 28 (25.7) | 10 (16.1) | 18 (38.3) | |
| Solid type | 4 (3.7) | − (0.0) | 4 (8.5) | 0.0009 |
| Ploidy, no. (%) | ||||
| Diploid | 22 (46.8) | 6 (24.0) | 16 (72.7) | |
| Aneuploid | 25 (53.2) | 19 (76.0) | 6 (27.3) | 0.001 |
| Adjuvant chemotherapy, no. (%) | ||||
| No | 87 (79.8) | 49 (79.0) | 38 (80.9) | |
| Yes | 22 (20.2) | 13† (21.0) | 9‡ (19.2) | 1.0 |
| Life status, no. (%) | ||||
| Alive | 72 (66.1) | 33 (53.2) | 39 (82.9) | |
| Dead | 37 (33.9) | 29 (46.8) | 8 (17.0) | 0.001 |
| Recurrence, no. (%) | ||||
| No | 74 (67.9) | 35 (56.5) | 39 (82.9) | |
| Yes | 36 (33.1) | 27 (43.6) | 8 (17.0) | 0.004 |
*Fisher’s exact test.
†Four patients had stage II disease, 9 had stage III disease.
‡Three patients had stage II disease, 6 had stage III disease.