Table 1.
Cases with p53 Mutations Including Type of Mutation
| Case | Codon (exon) | Mutation | Change in amino acid |
|---|---|---|---|
| LB14 | 158 (5) | CGC→CAC | Arg→His |
| LB21 | 244 (7) | GGC→GAC | Gly→Asp |
| LB47 | 273 (8) | CGT→CAT | Arg→His |
| LB48 | 273 (8) | CGT→CAT | Arg→His |
| LB54 | 270 (8) | TTT→CTT | Phe→Leu |
| LB146 | 245 (7) | GGC→AGC | Gly→Ser |
| LB194 | 157 (5) | GTC→TTC | Val→Phe |
| LB271 | 135 (5) | TGC→TTC | Cys→Phe |
| LB322 | 213 (6) | CGA→CGG | Arg→Arg |
| LB415 | 213 (6) | CGA→CGG | Arg→Arg |
| BL13 | 196 (6) | CGA→TGA | Arg→STOP |
| BL172 | 248 (7) | CGG→CAG | Arg→Gln |
| BL324 | 215 (6) | AGT→CGT | Ser→Arg |
| 213 (6) | CGA→CGG | Arg→Arg |