Table 1.
Allelic Loss at 18q21.1 (D18S4747–D18S539) and Expression of SMAD4, SMAD2, and DCC in 60 Serous Ovarian Carcinomas
| Case no. | 18q21.1* | SMAD4† | SMD2† | DCC† |
|---|---|---|---|---|
| 256 | − | + | + | + |
| 405 | − | + | + | + |
| 784 | − | + | + | + |
| 1154 | − | + | + | + |
| 428 | − | + | + | − |
| 1121 | − | + | + | − |
| 859 | − | + | − | − |
| 780 | − | + | − | − |
| 1217 | − | + | − | − |
| 761 | − | + | − | + |
| 981 | − | + | − | + |
| 787 | − | + | − | + |
| 810 | − | + | − | + |
| 1182 | − | + | − | + |
| 983 | − | − | + | + |
| 412 | − | − | + | + |
| 223 | − | − | + | − |
| 723 | − | − | + | − |
| 1117 | − | − | + | − |
| 1183 | − | − | + | − |
| 1164 | − | − | + | − |
| 755 | − | − | − | + |
| 1078 | − | − | − | + |
| 750 | − | − | − | − |
| 1151 | − | 0 | 0 | 0 |
| 277 | + | + | + | + |
| 402 | + | + | + | + |
| 1027 | + | + | + | + |
| 823 | + | + | + | + |
| 1130 | + | + | + | + |
| 852 | + | + | + | + |
| 250 | + | + | + | + |
| 261 | + | + | + | + |
| 793 | + | + | + | + |
| 796 | + | + | + | + |
| 818 | + | + | + | + |
| 821 | + | + | + | + |
| 849 | + | + | + | + |
| 984 | + | + | + | + |
| 960 | + | + | + | + |
| 989 | + | + | + | + |
| 994 | + | + | + | + |
| 1053 | + | + | + | + |
| 1129 | + | + | + | + |
| 1180 | + | + | + | + |
| 1192 | + | + | + | + |
| 1106 | + | + | + | − |
| 779 | + | + | + | − |
| 846 | + | + | − | + |
| 201 | + | + | − | + |
| 828 | + | + | − | + |
| 1097 | + | + | − | + |
| 1184 | + | + | − | − |
| 1185 | + | − | + | + |
| 1195 | + | − | + | + |
| 795 | + | − | + | − |
| 769 | + | − | + | − |
| 995 | + | − | + | − |
| 1136 | + | − | + | − |
| 1124 | + | − | − | + |
*−, LOH at 18q21.1; +, no LOH at 18q21.1.
†+, positive immunoreactivity; −, negative immunoreactivity; 0, not interpretable.