Table 2.
Loss of Expression of SMAD4, SMAD2, or DCC in Tumors with LOH (n = 24) and without LOH at 18q21.1 (D18S474–D18S539) (n = 35)
LOH | No LOH | P value | |
---|---|---|---|
SMAD4 | 10/24 = 42% | 7/35 = 20% | 0.086 |
SMAD2 | 11/24 = 46% | 6/35 = 17% | 0.022 |
DCC | 11/24 = 46% | 7/35 = 20% | 0.046 |
SMAD4, SMAD2, and/or DCC | 20/24 = 83% | 14/35 = 40% | 0.0012 |