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Modulation of IL-8 (A), MCP-1 (B), and IL-6 (C) secretion by IFN-γ. HRPE cells (HRPE), monocytes (Mo), and HRPE cell/monocyte co-cultures (HRPE + Mo) were incubated in the medium containing IFN-γ (1000 U/ml), either alone or in combination with thrombin for 24 hours. Supernatants were collected and IL-8, MCP-1, and IL-6 protein levels in supernatants were measured by ELISA (n = 3).
