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. 2001 Sep;159(3):831–835. doi: 10.1016/S0002-9440(10)61758-0

Figure 2.

Figure 2.

Immunohistochemical staining for E-Cadherin in normal bladder epithelium (A) and bladder cancers (B–D). The papillary cancer in B was scored as 2+ (1+ for intensity and 3+ for extent) and the infiltrating cancer in C was scored as 1+ (both extent and intensity). D: An infiltrating cancer with heterogeneous staining for E-Cadherin (scored as 2+ for both extent and intensity). All neoplasms (B–D) have methylation of e-cadherin.