Table 2.
HPV DNA Detection in Penile Condyloma, Dysplasia, and Carcinoma
| Diagnosis | n | HPV-positive | Single HPV type low risk | Single HPV type high risk | Multiple HPV types high risk | Multiple HPV types low and high risk | X types | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % | n | %* | n | %* | n | %* | n | %* | n | %* | ||
| Condyloma | 12 | 12 | 100.0 | 11 | 91.7 | 1 | 8.3 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dysplasia | 30 | 27 | 90.0 | 5 | 18.5 | 16 | 59.3 | 4 | 14.8 | 2 | 7.4 | 0 | 0 |
| All benign cases | 42 | 39 | 92.8 | 16 | 41.0 | 17 | 43.6 | 4 | 10.3 | 2 | 5.1 | 0 | 0 |
| Keratinizing scc | 106 | 37 | 34.9 | 0 | 0 | 23 | 62.1 | 4 | 10.8 | 4 | 10.8 | 6 | 16.2 |
| Verrucous scc | 12 | 4 | 33.3 | 1 | 25.0 | 2 | 50.0 | 0 | 0 | 0 | 0 | 1 | 25.0 |
| Basaloid scc | 15 | 12 | 80.0 | 0 | 0 | 11 | 91.7 | 1 | 8.3 | 0 | 0 | 0 | 0 |
| Warty scc | 5 | 5 | 100.0 | 0 | 0 | 4 | 80.0 | 0 | 0 | 1 | 20.0 | 0 | 0 |
| Clear cell scc | 2 | 1 | 50.0 | 0 | 0 | 1 | 100.0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Sarcomatoid scc | 1 | 0 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Metastatic scc | 1 | 1 | 100.0 | 0 | 0 | 1 | 100.0 | 0 | 0 | 0 | 0 | 0 | 0 |
| All cancer cases | 142 | 60 | 42.2 | 1 | 1.6 | 42 | 70.0 | 5 | 8.3 | 5 | 8.3 | 7 | 11.6 |
*, Percent of HPV-positive cases.
scc, Squamous cell carcinoma.
Low risk HPVs detected: 6,11,74; High risk HPVs detected: 16,18,31,33,35,39,44,45,51,52,53,54,58,66,68,70; X types: unknown HPV types.