Table 2.
Distribution Profile of Unipotent and Bipotent ED 14 FLEP Cells before Transplantation and Cell Clusters in the Liver 6 Months after Transplantation
| Phenotypic expression of isolated ED 14 FLEP cells before transplantation | ||
|---|---|---|
| Hepatocytic (AFP+) | Ductular (CK-19+) | Bipotential (AFP+/CK-19+) |
| 88% | 9% | 3% |
| Morphologic appearance of cell clusters derived from ED 14 FLEP cells six months after transplantation | |||
|---|---|---|---|
| Hepatocytic | Ductular | Mixed | Endothelial |
| 31%* | 5% | 56% | 7% |
*Approximately one-half of these clusters were very small and in the vicinity immediately adjacent to large clusters of mixed phenotype containing both hepatocytes and small epithelial cells in mature duct structures and appeared to result from reseeding of the liver from proliferating cells in these large mixed clusters.