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. 2001 Oct;159(4):1555–1566. doi: 10.1016/S0002-9440(10)62540-0

Figure 4.

Figure 4.

Graph showing the mean collagen matrix area for HRPE seeded on two-dimensional collagen matrices either in the presence or absence of antibodies directed against MMP-1, -2, -3, or -9. At no time point was there a significant difference (P > 0.05) between control and any MMP antibody-treated groups. Significant inhibition of contraction occurred at day 1 in matrices containing the antibody (10 μg/ml) directed against the β-1 integrin subunit (MCA 1188; P < 0.05; n = 6).