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Ultrastructural localizations of endothelin A receptor (ETAR) and endothelin B receptor (ETBR) in cirrhotic liver, by immunogold electron microscopy. a: Immunogold particles showing the presence of ETAR are hardly seen on sinusoidal endothelial cells (SECs) and hepatic stellate cells (HSCs). b: ETBRs are strongly expressed on the luminal sites of HSCs as well as SECs. e: sinusoidal endothelial cell. I: Ito cell (hepatic stellate cell). Scale bar, 1 μm. Uranyl acetate stain.
