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Mortality of PbA-infected mice. A: Survival of PbA-infected mice in days after infection (n = 10). B: Temperature on days 7 to 8 after PbA infection. Infected CD40−/− and CD40L−/− are significantly different from the +/+ (P < 0.05). C: Temperature on day 7 after infection in infected +/+ mice treated with hamster nonimmune IgG (nIgG) or anti-CD40L mAb on day 6. The two groups are significantly different (P < 0.05).
