Figure 3.
Cytogenetic features of PAC120 xenograft. A: Reconstitution of the karyotype evolution; a first group of alterations observed in two copies occurred before endoreduplication; another group of alterations observed in only one copy, in addition to the three copies of the parental homologous chromosome, indicating that the alterations occurred after endoreduplication; for five rearrangements, this classification was not possible. B: Reconstitution of chromosomes 1 and 11 after painting.