Table 2.
Allelic Imbalances on Six Chromosomal Regions in DNA from Tumor Samples
| Chromosome location Polymorphic loci studied | 8p21-p22 D8S133 D8S261 | 16q24 D16S507 | 10q22-q23 D10S541 D10S1765 | 13q12-q13 D13S153 D13S171 D13S2491 | 17q21 D17S800 D17S855 | 18q21 D18S39 D18S42 |
|---|---|---|---|---|---|---|
| DNA origin | ||||||
| At the diagnosis | AI† | AI | no AI | no AI | no AI | no AI |
| Lung metastasis* | ||||||
| At the recurrence | AI | AI | AI | AI | AI | AI |
| Primary tumor‡ | ||||||
| PAC120 xenograft | AI | AI | AI | AI | AI | AI |
*Obtained from corresponding microdissected histological preparations, as described in Materials and Methods.
†AI, allelic imbalance.
‡Second resection.