Table 1.

Effects on Animal and Uterine Weights of Treatment with SERMs

Age of mouse (days)	Controls	Tamoxifen	Toremifene	Raloxifene
6
Body wt (g)	4.24 ± 0.13	4.47 ± 0.24	3.56 ± 0.24	4.20 ± 0.09
Uterine wt*	0.24 ± 0.03	0.48 ± 0.05†	0.45 ± 0.04†	0.36 ± 0.03†
42
Body wt (g)	28.4 ± 0.80	27.5 ± 0.38	27.1 ± 0.48	28.3 ± 2.47
Uterine wt*	0.63 ± 0.06	0.39 ± 0.04†	0.43 ± 0.05†	0.69 ± 0.11
90
Body wt (g)	32.2 ± 0.60	29.1 ± 0.72	35.3 ± 2.14	30.0 ± 0.86
Uterine wt*	0.62 ± 0.05	0.38 ± 0.05†	0.50 ± 0.03	0.77 ± 0.07†

*Mean uterine weight expressed as percentage of body weight.

^†Statistically significant at the 5% level.