Skip to main content
. 2001 Dec;159(6):2187–2197. doi: 10.1016/S0002-9440(10)63070-2

Figure 2.

Figure 2.

Phagocytosis of myelin by resident endoneurial macrophages. A and B: Adjacent semithin serial sections double-stained for the TK-tsa transgene (red spots) and either ED1 (A) or myelin basic protein (B). A representative ED1-positive resident macrophage is shown that has phagocytosed myelin debris. The specificity of the stain is documented by semithin serial sections through another resident macrophage (C–E, asterisk) stained for ED1 (C), the TK-tsa transgene (D, red spot), and myelin basic protein (E). This resident macrophage does not contain myelin debris. Two (A and B) and 3 (C–E) days after crush lesion. A and B show additional phase contrast to delineate the morphology. Blue nuclear counterstain with DAPI. Scale bars, 10 μm (A and B); 15 μm (C).