Table 1.

Changes in TJ and AJ Protein Expression During Chronic Active IBD

Protein	Inactive IBD	Active IBD
		Epithelium away from PMN	Epithelium adjacent to PMN
Occludin	→	↓	↓↓
Claudin-1	→	→	↓↓
ZO-1	→	→	↓↓
JAM	→	→	↓↓
β-Catenin	→	→	↓↓
E-cadherin	→	→	↓↓

→, no changes compared to healthy control; ↓, diminished expression; ↓↓, strongly diminished expression.