Table 1.

Structures and Ab reactivity mediated by β1,6GnTs

Core 2, core 4, and I structures are synthesized by addition of β1,6-linked GlcNAc (bold) by C2GnT, C4GnT, and IGnT, respectively. Further galactosylation yields oligosaccharides reactive with mAb T305 (for core 2 oligosaccharides) or with α-I serum (for I reactive oligosaccharides).