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Time course of the renal involvement in TSLP transgenic mice. The figure illustrates the time course of the renal lesions in monthly intervals. Columns one and three represent the age-matched wild-type controls. The specimens are from mice at the age of ∼1 month (A–D), 2 months (E–H), 3 months (I–L), 5 months (M and N), and 7 months (O and P). Note the increase of mesangial matrix, which shows a severer course in female mice (arrow).
