Table 2.
Morphometric Data of the Renal Morphology
| Male wild type | Male TSLP transgenic | Female wild type | Female TSLP transgenic | |
|---|---|---|---|---|
| Mean matrix area per glomerulus (μm2 ± SEM) | 227.2 (±14.4) | 469.8† (±40.4) | 201.9 (±26.7) | 413† (±41.2) |
| Mean glomerular tuft area (μm2 ± SEM) | 1623 (±145) | 2223* (±218.5) | 1188 (±177.1) | 1450 (±199.1) |
| Percentage of glomerular matrix | 11% (±0.46) | 16%† (±0.74) | 12% (±0.93) | 19%† (±1.5) |
| Mean cells per glomerulus (±SEM) | 32.3 (±0.73) | 39.1† (±1.07) | 32.4 (±0.72) | 39* (±1.56) |
| Mean cells per glomerular tuft area (cells/μm2 ± SEM) | 0.016 (±0.0005) | 0.015 (±0.0006) | 0.019 (±0.0007) | 0.017 (±0.0007) |
| Area of macrophages per glomerulus (±SEM) | 20.2 (±4.8) | 136.1† (±24.2) | 7.7 (±3.4) | 79.2† (±19.8) |
| Percentage of glomerular macrophage area (±SEM) | 0.7% (±0.16) | 3.7%† (±0.4) | 0.3% (±0.1) | 2.7%† (±0.5) |
*P < 0.05, †P < 0.01 versus wild type.