Figure 3.

Up-regulation of inflammatory, fibrosis, proliferation, signaling, and stress response-associated genes. Genes up-regulated twofold or greater in HCV-associated cirrhosis compared to nondiseased liver tissue (A, C, E, G, I, and K) and AIH-associated cirrhosis (B, D, F, H, J, and L). Genes were categorized by association with inflammation (A and B); fibrosis (C and D); proliferation, growth, and regeneration (E and F); intracellular signaling and nuclear (G and H); stress response/oxidative stress (I and J); and uncategorized (K and L). Genes up-regulated in both comparisons are marked with asterisks.