Table 2.
Expression of ER-α and Ki-67 in Normal and Hyperplastic Foci in High-Risk and Normal Patients
| Total no. (foci) | Cases, no. (foci) | Controls, no. (foci) | % in cases (IQ) | % in controls (IQ) | P value* | |
|---|---|---|---|---|---|---|
| ER(N) | 43 (63) | 27 (41) | 16 (22) | 28.22 (12.18–45.98) | 20.10 (8.9–46.68) | 0.33 |
| ER(HUT) | 44 (131) | 25 (68) | 19 (63) | 57.00 (33.48–67.78) | 30.27 (19.75–52.5) | 0.008† |
| Ki-67(N) | 31 (43) | 16 (27) | 15 (16) | 0.70 (0–0.09) | 0.76 (0–4.38) | 0.35 |
| Ki-67(HUT) | 38 (87) | 16 (42) | 22 (45) | 3.82 (0.85–11.28) | 0.77 (0.0458–1.72) | <0.001† |
ER, Estrogen receptor α; N, normal lobules; IQ, interquartile range.
*Significant if P ≤ 0.05.
†Highly significant.