. 2002 Feb;160(2):655–666. doi: 10.1016/S0002-9440(10)64885-7

Table 2.

The Extent of Axonal Injury Was Significantly Higher in CM Patients Compared with Non-CM and Control Patients

Patient group	Brain region APP load ± SD				Average APP load (average ± SD)
Patient group	Cortex	Internal capsule	Pons	Cerebellum	Average APP load (average ± SD)
Control	0.2 ± 0.4	0.06 ± 0.2	0.005 ± 0.01	0	0.06 ± 0.2
Non-CM	0.5 ± 2.4	0.8 ± 2.1	0.04 ± 0.1	0.06 ± 0.1	0.3 ± 0.9
CM	0.4 ± 0.8	1.7 ± 3.2^†^§	0.9 ± 1.6^*^¶	0.3 ± 0.6^†	0.9 ± 1.3^‡^¶

*P < 0.01 compared with controls;

^†, P < 0.001 compared with controls;

^‡, P < 0.0001 compared with controls;

^§P < 0.01 compared with non-CM;

^¶P < 0.001 compared with non-CM. The amount of axonal damage or APP load was expressed as the area of tissue covered with APP staining divided by the total area of the section.