Table 2.
Invasion of ABX-IL8-Treated Melanoma Cells through Matrigel-Coated Filters
Cell lines | Treatment | Invasion cells (number/field ± SD) |
---|---|---|
TXM-13 | IgG | 184 ± 3 |
TXM-13 | ABX-IL8 | 45 ± 10 (P < 0.05) |
A375SM | IgG | 125 ± 43 |
A375SM | ABX-IL8 | 12 ± 1 (P < 0.01) |
ABX-IL8-treated and untreated melanoma cells were assayed for their potential to penetrate through Matrigel-coated filters. Melanoma cells (2 × 105) were placed in the upper chamber. After 22 hours of incubation, the cells on the lower surface of the filter were stained and counted.