Table 1.
p27Kip1 Protein Expression in Acquired Immune Deficiency Syndrome-Related Non-Hodgkin’s Lymphomas (AIDS-NHL)
| Percentage of neoplastic cells p27Kip1-positive | ||||||
|---|---|---|---|---|---|---|
| 0% | <10% | 10–24% | 25–49% | 50–74% | >75% | |
| Systemic AIDS-NHL* | ||||||
| BL (n = 29) | 25 | 0 | 0 | 0 | 2 | 2 |
| LNCCL (n = 33) | 32 | 1 | 0 | 0 | 0 | 0 |
| IBL (n = 24) | 5 | 2 | 1 | 5 | 5 | 6 |
| AIDS-PCNSL† | ||||||
| LNCCL (n = 2) | 1 | 0 | 0 | 1 | 0 | 0 |
| LNCCL/IBL (n = 4) | 2 | 1 | 0 | 1 | 0 | 0 |
| IBL (n = 14) | 4 | 0 | 2 | 3 | 5 | 0 |
Abbreviations: BL, Burkitt’s lymphoma; LNCCL, large noncleaved cell lymphoma; IBL, immunoblastic lymphoma; PCNSL, primary central nervous system lymphoma.
*P value <0.01 comparing p27Kip1 expression (negative versus positive) for AIDS-IBL versus all other systemic AIDS-NHL.
†P value = 0.61 comparing p27Kip1 expression (negative versus positive) for AIDS-IBL versus all other AIDS-PCNSL.