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A: Treatment of SW579 cells with recombinant LZ-TRAIL (50 to 200 ng/ml) for 18 hours resulted in higher survival in the presence of 10% FCS (squares) that in serum-free medium (triangles). Cell survival was quantified with the MTT assay. B: The IGF-1 receptor-neutralizing antibody aIR3 (2 μg/ml) potentiated the apoptosis-inducing effect of LZ-TRAIL (50 ng/ml) against SW579 cells in 10% FCS (MTT assay).
