Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A: Wortmannin (W) (5 μmol/L) increased the sensitivity of parental SW579 cells to LZ-TRAIL (50 ng/ml), suggesting that constitutive PI-3K activity is present in thyroid carcinoma cells and has an anti-apoptotic role. B: Wortmannin (5 μmol/L) exerted a similar sensitizing effect on the TRAIL-resistant SW579-TR cells treated with a higher concentration of LZ-TRAIL (300 ng/ml). Cell survival was quantified with the MTT assay.
